Five running backs sit at the epicenter of 2025 fantasy upside: Chase Brown, Kenneth Walker III, Omarion Hampton, D'Andre Swift, and R.J. Harvey. Each is paired with a favorable ADP, and all have a plausible path to finishing among the top scorers at their position by season’s end. Brown, Walker, Hampton, Swift, and Harvey are presented not as one-off breakouts but as versatile, scheme-friendly backs with legitimate league-winning potential if their roles hold or expand, even in uncertain backfields.

Chase Brown's late-season breakout for Cincinnati showcased a lead-back ceiling, averaging among the league's top points per game over an eight-game stretch. Kenneth Walker III has flashed elite efficiency and big-play ability when healthy, and Seattle's shift toward a run-first framework under Klint Kubiak could unlock a top-8 ceiling in 2025. Omarion Hampton lands in a Denver offense investing in the run and a versatile receiving game, making him a strong hit in the right passing-down role. D’Andre Swift's career arc—juggling multiple systems and roles—still carries a high ceiling if Chicago leans into zone runs and maximizes his multi-week usage. Finally, R.J. Harvey arrives with breakout speed and receiving chops in a Denver backfield that could stabilize behind a more predictable ground game, boosting his chances for a top-10 finish if he leads carries and catches on early downs.

ADP ranges from early fourth-round to mid-rounds, underscoring the value of each on draft day. The headline takeaway: these five backs offer clear, attainable routes to league-winning weeks, provided health and opportunity align with their teams’ evolving schemes and offensive lines.

Caleb Williams entered Chicago with fan patience thinning after a rocky camp, highlighted by an early interception in 1-on-1 drills and a botched pitch to D’Andre Swift that stoked social-media backlash. The Bears plan to roll Williams into the second preseason matchup vs. Buffalo, and the Week 1 regular-season clash with Minnesota looms as the real test. Williams’ rookie year teased upside, but 68 sacks and a 6.3-yard average per attempt undercut his fantasy ceiling. The Swift pairing adds a valuable safety valve, but line play and rhythm remain variables. Williams will need cleaner mechanics and more efficient throws to justify late-round quarterback upside; if not, volatility could limit early-season fantasy returns until the line and scheme stabilize.

Williams flashed in spurts for Chicago last year, finishing with 3,541 passing yards, 20 TDs, and 6 INTs across 17 starts, yet his sack rate and pass efficiency lagged peers. Preseason matchups and progress in practice will be critical barometers for fantasy managers weighing him as a potential QB2 with upside. Swift’s presence offers a meaningful safety net in the backfield, potentially softening the hit from a less-than-elite offensive line as Williams grows into the pro game. The coming weeks will shape Williams’ volatility into a clearer fantasy profile.

TreVeyon Henderson lands in New England with a real shot to seize a workhorse role behind a retooled offense. His speed (4.43) and pass-blocking profile offer an on-field path to heavy early-down work, even as the backfield competition evolves under new coaching. D'Andre Swift projects to steady volume in Chicago, where Ben Johnson’s Detroit-era history hints at efficient volume even if Chicago adds more mouths to feed. Pollard’s ceiling remains high if he fends off Tyjae Spears and a more balanced Titans attack, while Brian Robinson Jr. should anchor Washington’s backfield ahead of a healthier offense. Tank Bigsby, Tank Bigsby’s surge in Jacksonville pits him against Etienne for early-down duties, with Bigsby flashing downhill efficiency to challenge for a bigger slice of the carry pie. Ashton Jeanty’s draft landing in Las Vegas signals an immediate high-leverage role, and Ashton could become a staple in fantasy lineups quickly if the Raiders’ offense hits its stride. In short, five sneaky workhorses—Henderson, Swift, Pollard, Robinson Jr., Bigsby—plus late-rounds like Jeanty and Monangai, carve a realistic path to 200–250 carry seasons in 2025, with uphill odds and big upside depending on health and coaching. The 2024 season’s multi-backbird trend shows volume still matters, and a handful of sleepers can vault into bell-cow territory with the right circumstances.